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Kikuchi disease
Kikuchi-Fujimoto disease (KFD) was described in 1972 in Japan. It is also known as Kikuchi disease, histiocytic necrotizing lymphadenitis, Kikuchi necrotizing lymphadenitis, phagocytic necrotizing lymphadenitis, subacute necrotizing lymphadenitis, and necrotizing lymphadenitis.
It was first described in Japan by Dr Masahiro Kikuchi in 1972〔Kikuchi M. Lymphadenitis showing focal reticulum cell hyperplasia with nuclear debris and phagocytes. ''Acta Hematol Jpn'' 1972;35:379–80.〕 and independently by Y. Fujimoto.
==Epidemiology==
Kikuchi-Fujimoto disease (KFD) is a rare, self-limiting disorder that typically affects the cervical lymph nodes. Recognition of this condition is crucial, especially because it can easily be mistaken for tuberculosis, lymphoma, or even adenocarcinoma. Awareness of this disorder will help prevent misdiagnosis and inappropriate treatment.〔
Kikuchi's disease is a very rare disease and mainly seen in Japan. Isolated cases are reported in America, Europe and Asia. It is mainly a disease of young adults (mean age, 20–30 years), with a slight bias towards females. The cause of this disease is not known although infectious and autoimmune etiologies have been proposed. Course of the disease is generally benign and self-limiting. Lymphadenopathy most often resolves over several weeks to six months. Recurrence rate is about 3%. Mortality is extremely rare and usually due to hepatic, respiratory, or cardiac failure.
抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』
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